Somehow, no one - including the manufacturer - do not write that (quote) should not be used with medicines that contain metal ions (calcium, magnesium, iron) because lipoic acid's ability to bind metals. In acute need for drugs recommended to keep a certain time interval (a minimum of 2 hours). This information I dug yourself by reading a ton of articles about alpha lipoic acid - in the search for the causes of the renewed arrhythmia. I on a regular basis drink magnesium preparations - my arrhythmia caused by the constant lack of magnesium in the body, and he is known to be very easily deduced, it must be continually replenished. I could not understand why I was again plagued by cramps at night, why resumed arrhythmia - until then, until I realized that in the past two months, combining ALA with magnesium, I just did not give a chance to magnesium. Yes, to be honest: sugar cravings it reduces it, I also felt, but it is worth to point to all of the risks, not to get the opposite effect. In my case, ALA did not improve heart function, and vice versa.